Dr. Andrey S. Shaw is an Emil R. Unanue Professor of Pathology and Immunology at Washington University in St. Louis. He is the Head of the Division of Immunobiology and an Investigator of the Howard Hughes Medical Institute. Dr. Shaw is the editor of Molecular and Cellular Biology, a journal published by the American Society for Microbiology. He currently serves on the Immunology Program Steering Committee and the Curriculum Committee at Washington University Medical School. He is the recipient of NIH MERIT Award and numerous Distinguished Service Teaching Awards from the Medical School classes of Washington University.
Dr. Shaw attended medical school at Columbia University College of Physicians and Surgeons. After completing his residency in pathology at Yale-New Haven Hospital, he went on to complete a post-doctoral fellowship in the Department of Pathology and the Department of Cell Biology at Yale.
Dr. Shaw’s current work focuses podocytes and the genetic defects that can compromise the cells’ function in human patients. Dr. Shaw has already found that mutations which produce CD2AP protein deficiency can cause kidney disease, but he speculates that many other genes may be involved.
Selected Publications:
Cemerski S, Das J, Locasale J. Arnold P, Giurisato E, Markiewicz MA, Fremont D, Allen PM, Chakraborty AK, Shaw AS. The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse. Immunity 2007; 26:345-355
Locasale JW, Shaw AS, Chakraborty AK. Scaffold proteins confer diverse regulatory properties to protein kinase cascades. Proc Natl Acad Sci 2007; 104:13307-13312.
Akilesh S, Christianson GJ, Roopenian DC, Shaw AS. Neonatal FcR expression in bone marrow-derived cells functions to protect serum IgG from catabolism. J Immunol 2007;179:4580-4588. |
